The screw cap can be tightly closed as the membrane permits an automatic sterile gas exchange, allowing safe pressure equalisation during the autoclave cycle, and at the same time ensuring the sterility of the bottle contents.

Large exposed sterile-filter surface area allows efficient gas exchange rates for cell culture applications in bottles and shaker flasks. DURAN® Original GL Screw Capped Laboratory bottles are ideal containers for sterilising and storing media or buffer solutions.

However, it is strongly recommended that during the autoclaving cycle the caps are only loosely tightened.

Heating times are reduced if the steam is easily able to penetrate the contents of the bottle.

Loose caps also reduce the risk of failure due to pressure build up inside the bottle, which can reach 400 kPa (absolute).

The screw cap can be tightly closed as the membrane permits an automatic sterile gas exchange, allowing safe pressure equalisation during the autoclave cycle, and at the same time ensuring the sterility of the bottle contents.

Large exposed sterile-filter surface area allows efficient gas exchange rates for cell culture applications in bottles and shaker flasks. DURAN® Original GL Screw Capped Laboratory bottles are ideal containers for sterilising and storing media or buffer solutions.

However, it is strongly recommended that during the autoclaving cycle the caps are only loosely tightened.

Heating times are reduced if the steam is easily able to penetrate the contents of the bottle.

Loose caps also reduce the risk of failure due to pressure build up inside the bottle, which can reach 400 kPa (absolute).